Paul is a biochemist with a Ph.D. from the ETH Zürich. He joined Roche’s Pharma Research in 1975 and his work for 25 years in several therapeutic areas led to a notable track-record in the discovery of novel drug candidates/drugs and in the management of a global discovery organization as head of thrombosis, dermatology, infectious diseases as well as novel biological technologies. He was a member of Roche’s Global Research Management Team and of the Global Disease Area Strategy Team. In 2000, upon the strategic decision of Roche to terminate infectious diseases research, but the desire to save the expertise and development candidates in this field, he was instrumental in the creation of the spin-off biotech company Basilea Pharmaceutica and acted as its first CEO and CSO. In 2003 he joined the Development Department of Arpida AG and acted from 2006 to 2008 as Head of Development. Since then, he became an entrepreneur in the pharmaceutical & medical device business and founded several companies, mainly focusing on anti-infectives, oncology and diabetes treatment.
Richard is a drug regulatory affairs professional with 25 years’ experience of product development and registration activities in Europe and the US for a broad range of new oncology and bio-tech medicines. He has hands-on experience of US and EU regulatory procedures. Leadership and communication skills. Organising, planning, problem-solving and negotiation skills. Capable of working both independently and as a member of an integrated team. Experience of dealing with people in an international environment. Ph.D. in Internal Medicine and MSc in Regulatory Affairs.
Pascal has 20 years’ experience in quality assurance and operational management of global clinical trials within pharmaceutical and medical device industry: experienced in study feasibility and budgeting, protocol development, submissions to regulatory authorities and ethical committees, site and study management, monitoring and auditing, vendor management and study logistics, data management, archiving, reporting, publishing and filing for marketing approval for phase I, II, III and IV trials, products quality review, management of batch documentation, QP/FvP batch release. Certified lead auditor. Performed numerous worldwide vendor audits against cGxP standards, including co-monitoring with CRAs. Prepared and hosted multiple FDA, Swissmedic & EMA license-to-operate and pre-approval inspections. BSc Telecommunication Engineering & MSc Clinical Research, in addition to regular quality assurance and regulatory training. Serial entrepreneur in human and animal healthcare start-ups.